By 1699, most of the Wando Indians had succumbed to smallpox and other diseases brought by the Europeans. The Sewee Indians, by 1715, were the only tribe left living along the coast north of Charleston Harbor and numbered around 67 men, women, and children. They were captured in 1716, shipped out of the colony, and sold as slaves. Today, some of the street names in old Mount Pleasant, such as Mataoka Street and Poaugh Lane, reflect this earlier American Indian heritage.
